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A Phase II Study of Daratumumab-Hyaluronidase for Chemotherapy-Relapsed/Refractory Minimal Residual Disease (MRD) in T Cell Acute Lymphoblastic Leukemia (T-ALL)

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A Phase II Study of Daratumumab-Hyaluronidase for Chemotherapy-Relapsed/Refractory Minimal Residual Disease (MRD) in T Cell Acute Lymphoblastic Leukemia (T-ALL)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Dec 2024

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At a glance

  • Drugs Cytarabine (Primary) ; Daratumumab (Primary) ; Daratumumab/hyaluronidase (Primary) ; Methotrexate (Primary) ; Methotrexate (Primary) ; Pegaspargase (Primary) ; Vincristine (Primary)
  • Indications Precursor T-cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use

    • Most Recent Events

    • 12 Dec 2024 Planned End Date changed from 31 Oct 2024 to 30 Jun 2027.
    • 12 Dec 2024 Planned primary completion date changed from 31 Oct 2024 to 30 Jun 2027.
    • 18 Dec 2023 Planned End Date changed from 1 Oct 2024 to 31 Oct 2024.

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