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Phase 3 trial of Atacicept for IgA Nephropathy (IGAN)

Trial Profile

Phase 3 trial of Atacicept for IgA Nephropathy (IGAN)

Status: Planning
Phase of Trial: Phase III

Latest Information Update: 18 Nov 2024

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At a glance

  • Drugs Atacicept (Primary)
  • Indications Autoimmune disorders; Glomerulonephritis; IgA nephropathy
  • Focus Registrational; Therapeutic Use
  • Acronyms PIONEER
  • Sponsors Vera Therapeutics
  • Most Recent Events

    • 11 Nov 2024 According to a Vera Therapeutics media release, company will present initial data from PIONEER study in 2025 and NEPTUNE Match, in partnership with Vera Therapeutics, will inform participants about the PIONEER study. PIONEER expands atacicept research into autoimmune kidney diseases, including IgAN, pMN, FSGS, and MCD, targeting anti-PLA2R and anti-nephrin antibodies. The program supports informed decisions about clinical trial participation.
    • 26 Oct 2024 According to a Vera Therapeutics media release, trial is divided in 2 cohorts Expanded IgAN populations and Anti-PLA2R and anti-nephrin podocytopathies.
    • 02 Oct 2024 According to a Vera Therapeutics media release, PIONEER study expands the investigation of atacicept into a broad definition of IgA nephropathy and into multiple autoimmune glomerular diseases.

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