Trial Profile

A Phase 1/1b Dose Escalation and Cohort Expansion Study of MGC018 in Combination With Checkpoint Inhibitor in Participants With Advanced Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 09 Jun 2025

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At a glance

Drugs Lorigerlimab (Primary) ; Vobramitamab duocarmazine (Primary)
Indications Liver cancer; Malignant melanoma; Ovarian cancer; Pancreatic cancer; Prostate cancer; Renal cell carcinoma; Solid tumours
Focus Adverse reactions
Sponsors MacroGenics

Most Recent Events

03 Jun 2025 Planned End Date changed from 1 Jun 2025 to 1 Oct 2025.
03 Jun 2025 Planned primary completion date changed from 1 Apr 2025 to 1 Jul 2025.
20 Nov 2024 Planned End Date changed from 1 Mar 2026 to 1 Jun 2025.

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