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A Phase 1/2, Open-Label, Dose-Escalation and Expansion Study of the Bruton Tyrosine Kinase-Targeted Protein-Degrader BGB-16673 in Chinese Patients With B-Cell Malignancies

Trial Profile

A Phase 1/2, Open-Label, Dose-Escalation and Expansion Study of the Bruton Tyrosine Kinase-Targeted Protein-Degrader BGB-16673 in Chinese Patients With B-Cell Malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Jun 2025

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At a glance

  • Drugs BGB-16673 (Primary)
  • Indications Chronic lymphocytic leukaemia; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions; First in man
  • Sponsors BeOne Medicines

Most Recent Events

  • 27 May 2025 According to BeOne Medicines media release, BeiGene is now called BeOne Medicines
  • 20 Apr 2025 Planned number of patients changed from 127 to 146.
  • 27 Feb 2025 According to a BeiGene media release, data readout from this trial is expected in 2026.

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