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A Non-randomised, Open-label, 2-part, Parallel-cohort Trial to Evaluate 1) Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of BI 456906 in Patients With Cirrhosis and Varying Degrees of Hepatic Impairment Relative to Healthy Subjects With and Without Overweight/Obesity and 2) Safety and Tolerability of Multiple Subcutaneous Doses of BI 456906 in Patients With Overweight/Obesity With Cirrhosis and Varying Degrees of Hepatic Impairment Relative to Patients With Overweight/Obesity Without Cirrhosis/Hepatic Impairment

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Trial Profile

A Non-randomised, Open-label, 2-part, Parallel-cohort Trial to Evaluate 1) Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of BI 456906 in Patients With Cirrhosis and Varying Degrees of Hepatic Impairment Relative to Healthy Subjects With and Without Overweight/Obesity and 2) Safety and Tolerability of Multiple Subcutaneous Doses of BI 456906 in Patients With Overweight/Obesity With Cirrhosis and Varying Degrees of Hepatic Impairment Relative to Patients With Overweight/Obesity Without Cirrhosis/Hepatic Impairment

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 19 Aug 2024

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At a glance

  • Drugs Survodutide (Primary)
  • Indications Obesity
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 05 Jan 2024 Status changed from active, no longer recruiting to completed.
  • 22 Nov 2023 Status changed from recruiting to active, no longer recruiting.
  • 18 Oct 2023 Planned End Date changed from 30 Dec 2023 to 29 Dec 2023.

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