Trial Profile

A Phase 1 Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 11 Oct 2025

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At a glance

Drugs PF 08046052 (Primary)
Indications Adenocarcinoma; Colorectal cancer; Head and neck cancer; Non-small cell lung cancer; Pancreatic ductal carcinoma; Solid tumours; Squamous cell cancer
Focus Adverse reactions
Sponsors Lava Therapeutics; Seagen

Most Recent Events

13 Aug 2025 Accoridng to a LAVA Therapeutics media release, trial is enrolling patients and currently underway in US and UK.
19 Jun 2025 Planned End Date changed from 3 Jul 2029 to 9 Jan 2030.
19 Jun 2025 Planned primary completion date changed from 3 Jul 2028 to 9 Jan 2029.

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