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A Phase 1b Study of Serabelisib in Combination with an Insulin Suppressing Diet (Study ISD) and with or Without Nab-paclitaxel in Adult Subjects with Advanced Solid Tumors with PIK3CA Mutations with or Without PTEN Loss

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A Phase 1b Study of Serabelisib in Combination with an Insulin Suppressing Diet (Study ISD) and with or Without Nab-paclitaxel in Adult Subjects with Advanced Solid Tumors with PIK3CA Mutations with or Without PTEN Loss

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Paclitaxel (Primary) ; Serabelisib (Primary)
  • Indications Adenocarcinoma; Clear cell sarcoma; Colon cancer; Colorectal cancer; Endometrial cancer; Ovarian cancer; Rectal cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors Faeth Therapeutics

    • Most Recent Events

    • 27 Feb 2025 Planned End Date changed from 1 Sep 2024 to 1 Dec 2025.
    • 27 Feb 2025 Planned primary completion date changed from 1 Sep 2024 to 1 Dec 2025.
    • 16 Jan 2024 Status changed from recruiting to active, no longer recruiting.

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