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A Phase Ia/Ib, First-in-Human, Open-Label, Multicenter, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Preliminary Efficacy of SG2501 in Subjects with Relapsed or Refractory Hematological Malignancies and Lymphoma.

Trial Profile

A Phase Ia/Ib, First-in-Human, Open-Label, Multicenter, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Preliminary Efficacy of SG2501 in Subjects with Relapsed or Refractory Hematological Malignancies and Lymphoma.

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs SG 2501 (Primary)
  • Indications Amyloid light-chain amyloidosis; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Hodgkin's disease; Multiple myeloma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions; First in man
  • Sponsors Hangzhou Sumgen Biotech

Most Recent Events

  • 18 Mar 2025 Status changed from recruiting to discontinued.
  • 10 Feb 2023 Planned End Date changed from 1 Sep 2024 to 30 Apr 2025.
  • 10 Feb 2023 Planned primary completion date changed from 1 Feb 2023 to 30 Dec 2024.

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