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A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Versus Placebo in Early Stage NSCLC Patients With Uncommon EGFR Mutations Following Complete Tumor Resection (REZILIENT4)

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Trial Profile

A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Versus Placebo in Early Stage NSCLC Patients With Uncommon EGFR Mutations Following Complete Tumor Resection (REZILIENT4)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 16 Oct 2026

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At a glance

  • Drugs Zipalertinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms REZILIENT4
  • Sponsors Taiho Oncology

Most Recent Events

  • 13 Oct 2026 Status changed from active, no longer recruiting to recruiting.
  • 26 Aug 2026 The protocol has been amended to change in treatment arms.
  • 23 Apr 2026 Status changed from recruiting to active, no longer recruiting.

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