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A Phase 1/2 Open-Label Intrathecal Administration of TSHA-105 to Determine the Safety and Efficacy in Subjects With SLC13A5 Citrate Transporter Disorder Caused by a Mutation in the SLC13A5 Gene.

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Trial Profile

A Phase 1/2 Open-Label Intrathecal Administration of TSHA-105 to Determine the Safety and Efficacy in Subjects With SLC13A5 Citrate Transporter Disorder Caused by a Mutation in the SLC13A5 Gene.

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Jul 2026

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At a glance

  • Drugs TSHA-105 (Primary)
  • Indications Epilepsy
  • Focus Adverse reactions
  • Sponsors Elpida Therapeutics

Most Recent Events

  • 30 Jun 2026 Planned initiation date changed from 1 Aug 2026 to 15 Jul 2026.
  • 30 Jun 2026 Status changed from not yet recruiting to recruiting.
  • 17 Jun 2026 Planned number of patients changed from 2 to 8.

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