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A Phase 1/2, Open -Label, Multicenter Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antineoplastic Activity of S095033 (MAT2A Inhibitor) in Combination With Paclitaxel in Participants With Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Trial Profile

A Phase 1/2, Open -Label, Multicenter Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antineoplastic Activity of S095033 (MAT2A Inhibitor) in Combination With Paclitaxel in Participants With Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I/II

Latest Information Update: 12 Dec 2022

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At a glance

  • Drugs Paclitaxel (Primary) ; S 095033 (Primary)
  • Indications Carcinoma; Oesophageal cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Servier
  • Most Recent Events

    • 05 Dec 2022 Planned primary completion date changed from 1 Dec 2025 to 1 Jun 2026.
    • 05 Dec 2022 Planned initiation date changed from 1 Aug 2022 to 1 May 2025.
    • 05 Dec 2022 Status changed from not yet recruiting to withdrawn prior to enrolment.

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