Trial Profile

Zanubrutinib (Brukinsa®) in Patients With Waldenström's Macroglobulinemia (WM), Chronic Lymphocytic Leukemia (CLL), Marginal Zone Lymphoma (MZL) and Follicular Lymphoma (FL) - a Prospective Multicenter Observational Cohort Study

Status: Recruiting

Phase of Trial: Phase IV

Latest Information Update: 10 Oct 2025

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At a glance

Drugs Zanubrutinib (Primary)
Indications Chronic lymphocytic leukaemia; Marginal zone B-cell lymphoma; Waldenstrom's macroglobulinaemia
Focus Therapeutic Use
Acronyms ARIADNE

23 Sep 2025 Planned number of patients changed from 605 to 705.
01 Oct 2024 Planned End Date changed from 1 Apr 2027 to 1 Aug 2028.
01 Oct 2024 Planned primary completion date changed from 1 Apr 2027 to 1 Aug 2028.

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