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An Open-label, Phase I Dose Escalation Followed by Dose Expansion Trial in Patients With Advanced Solid Tumours to Investigate Safety, Pharmacokinetics, and Efficacy and to Select the Dose for Further Development of BI 770371 in Combination With Ezabenlimab

Trial Profile

An Open-label, Phase I Dose Escalation Followed by Dose Expansion Trial in Patients With Advanced Solid Tumours to Investigate Safety, Pharmacokinetics, and Efficacy and to Select the Dose for Further Development of BI 770371 in Combination With Ezabenlimab

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 02 Jun 2025

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At a glance

  • Drugs BI 770371 (Primary) ; Ezabenlimab (Primary)
  • Indications Colorectal cancer; Ovarian cancer; Prostate cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 28 May 2025 Planned End Date changed from 30 Sep 2025 to 30 Sep 2026.
  • 22 May 2025 Results presented in a Boehringer Ingelheim Media Release.
  • 23 Apr 2025 According to a OSE Immunotherapeutics media release, company will present data from this study in an oral presentation at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting, taking place from June 1-5, 2025, in Chicago, Illinois.

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