A phase 1 trial evaluating MB-109 (combination of MB-101 (IL13R2targeted CAR T cell therapy) and MB-108 (C134 oncolytic virus)) for the treatment of recurrent glioblastoma (rGBM)
Latest Information Update: 13 Mar 2024
At a glance
- Drugs MB 109 (Primary)
- Indications Astrocytoma; Glioblastoma
- Focus Adverse reactions
- Sponsors Mustang Bio
Most Recent Events
- 11 Mar 2024 According to Mustang Bio media release, the company evaluating plans to initiate this trial and request orphan drug designation for GBM, subject to resource allocation, in 2024.
- 26 Oct 2023 According to Mustang Bio media release, the U.S. Food and Drug Administration (FDA) has accepted the IND application of MB-109 for the treatment of recurrent glioblastoma (GBM) and high-grade astrocytoma.
- 26 Oct 2023 According to Mustang Bio media release, this trial is expected to begin enrolling patients in 2024.