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A Phase I, Open-label, Fixed-sequence, Two-period, Crossover, Drug-drug Interaction Study to Investigate the Effect of Efavirenz on the Pharmacokinetics of Ganaplacide and Lumefantrine Combination in Healthy Participants

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Trial Profile

A Phase I, Open-label, Fixed-sequence, Two-period, Crossover, Drug-drug Interaction Study to Investigate the Effect of Efavirenz on the Pharmacokinetics of Ganaplacide and Lumefantrine Combination in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 Jan 2023

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At a glance

  • Drugs Efavirenz (Primary) ; Ganaplacide (Primary) ; Lumefantrine (Primary)
  • Indications Falciparum malaria
  • Focus Pharmacokinetics
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 11 Jan 2023 Status changed from recruiting to completed.
  • 02 Nov 2022 Planned number of patients changed from 20 to 60.
  • 02 Nov 2022 Planned End Date changed from 27 Jun 2022 to 22 Nov 2022.

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