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A Phase I, Open-Label, Multi-Center, Dose Finding Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies

Trial Profile

A Phase I, Open-Label, Multi-Center, Dose Finding Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 24 Jul 2024

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At a glance

  • Drugs ATG 018 (Primary)
  • Indications Diffuse large B cell lymphoma; Haematological malignancies; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Solid tumours
  • Focus Adverse reactions
  • Acronyms ATRIUM
  • Sponsors Antengene Corporation
  • Most Recent Events

    • 18 Jul 2024 Status changed from recruiting to discontinued. ( Lack of efficacy of study compound)
    • 19 Apr 2024 Planned primary completion date changed from 31 Mar 2024 to 30 Jun 2024.
    • 16 Aug 2022 According to an Antengene Corporation media release, the first patient has been dosed in this trial

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