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A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Study to Assess the Safety, Tolerability, PD and PK of RLS-0071 in Healthy Adult Subjects After Challenge With Inhaled Lipopolysaccharide (LPS)

Trial Profile

A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Study to Assess the Safety, Tolerability, PD and PK of RLS-0071 in Healthy Adult Subjects After Challenge With Inhaled Lipopolysaccharide (LPS)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 May 2025

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At a glance

  • Drugs Pegtarazimod (Primary) ; Lipopolysaccharide
  • Indications Acute lung injury; Asthma; Brain hypoxia-ischaemia; Brain injuries
  • Focus Pharmacodynamics; Proof of concept
  • Sponsors ReAlta Life Sciences

Most Recent Events

  • 19 May 2025 According to a ReAlta Life Sciences media release, a poster presentation featuring new analysis of clinical data using samples from this trial, and AE-COPD program will be presented at the American Thoracic Society (ATS) 2025 International Conference, taking place May 18-21, 2025 in San Francisco.
  • 22 May 2024 Results presented at the 120th International Conference of the American Thoracic Society
  • 05 Sep 2023 According to a ReAlta Life Sciences media release, additional clinical data from this trial will be presented at the European Respiratory Society 2023 International Congress taking place in Milan, Italy on 9-13 September, 2023, data will be presented by the Prof. Dr. Jens M. Hohlfeld.

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