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A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase IIIb Study Evaluating the Effect of Inclisiran on Atherosclerotic Plaque Progression Assessed by Coronary Computed Tomography Angiography (CCTA) in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (VICTORION-PLAQUE)

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Trial Profile

A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase IIIb Study Evaluating the Effect of Inclisiran on Atherosclerotic Plaque Progression Assessed by Coronary Computed Tomography Angiography (CCTA) in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (VICTORION-PLAQUE)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs Inclisiran (Primary) ; HMG-CoA reductase inhibitors
  • Indications Atherosclerosis; Coronary artery disease
  • Focus Registrational; Therapeutic Use
  • Acronyms V-PLAQUE; VICTORION-PLAQUE
  • Sponsors Novartis; Novartis Pharmaceuticals

Most Recent Events

  • 03 Feb 2025 Status changed from recruiting to active, no longer recruiting.
  • 09 Jul 2024 Planned End Date changed from 15 Jan 2027 to 25 Jan 2027.
  • 09 Jul 2024 Planned primary completion date changed from 7 Jan 2027 to 25 Jan 2027.

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