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A Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION717 in Patients With Prion Disease

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Trial Profile

A Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION717 in Patients With Prion Disease

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 31 Dec 2024

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At a glance

  • Drugs ION 717 (Primary)
  • Indications Prion diseases
  • Focus Adverse reactions; First in man
  • Sponsors Ionis Pharmaceuticals

Most Recent Events

  • 27 Dec 2024 Planned End Date changed from 1 Jun 2027 to 1 Jul 2027.
  • 27 Dec 2024 Planned primary completion date changed from 1 Mar 2025 to 1 Jul 2025.
  • 27 Dec 2024 Status changed from recruiting to active, no longer recruiting.

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