Trial Profile

A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 27 Oct 2025

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At a glance

Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Cladribine (Primary) ; Cytarabine (Primary) ; Venetoclax (Primary)
Indications Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
Focus Therapeutic Use

27 Sep 2024 Planned End Date changed from 1 Feb 2025 to 1 Dec 2025.
27 Sep 2024 Planned primary completion date changed from 1 Feb 2025 to 1 Dec 2025.
11 Jan 2024 Planned End Date changed from 1 Feb 2024 to 1 Feb 2025.

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