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A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SKB315 for Injection in Patients With Advanced Solid Tumors Expressing Claudin18.2

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Trial Profile

A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SKB315 for Injection in Patients With Advanced Solid Tumors Expressing Claudin18.2

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Nov 2025

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At a glance

  • Drugs MK 1200 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Sichuan Kelun Pharmaceutical Research Institute; Sichuan Kelun-Biotech Biopharmaceutical

Most Recent Events

  • 17 Nov 2025 Planned number of patients changed from 206 to 246.
  • 17 Nov 2025 Planned End Date changed from 28 Feb 2026 to 30 Jun 2028.
  • 17 Nov 2025 Planned primary completion date changed from 31 Dec 2024 to 30 Jun 2026.

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