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A Phase I, Open-label, Multicenter Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Single and Multiple Doses of Oral Administration of HS-10382 in Patients With Chronic Myeloid Leukemia

Trial Profile

A Phase I, Open-label, Multicenter Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Single and Multiple Doses of Oral Administration of HS-10382 in Patients With Chronic Myeloid Leukemia

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Jan 2024

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At a glance

  • Drugs TRN-000632 (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Jiangsu Hansoh Pharmaceutical

Most Recent Events

  • 04 Jan 2024 According to a Terns Pharmaceuticals media release, the CARDINAL study design leverages insights from this trial in China, which support a starting dose that appears safe and clinically active based on emerging early clinical data.
  • 15 Jun 2023 Trial design presented at the 28th Congress of the European Haematology Association.
  • 06 Jun 2023 Trial design, presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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