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A Phase 1 Study of BET Bromodomain Inhibitor ZEN003694 in Combination With the CDK4/6 Inhibitor Abemaciclib in Patients With NUT Carcinoma, Breast Cancer and Other Solid Tumors

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Trial Profile

A Phase 1 Study of BET Bromodomain Inhibitor ZEN003694 in Combination With the CDK4/6 Inhibitor Abemaciclib in Patients With NUT Carcinoma, Breast Cancer and Other Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 29 Jul 2025

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At a glance

  • Drugs Abemaciclib (Primary) ; ZEN 3694 (Primary)
  • Indications Carcinoma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 16 Jul 2025 Planned End Date changed from 1 Jun 2025 to 1 Jun 2026.
  • 16 Jul 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Jun 2026.
  • 01 Aug 2023 Planned initiation date changed from 12 Aug 2022 to 29 Oct 2023.

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