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Randomized, Open-Label Study of the Bria-IMT Regimen and Check Point Inhibitor vs Physicians' Choice in Advanced Metastatic Breast Cancer

Trial Profile

Randomized, Open-Label Study of the Bria-IMT Regimen and Check Point Inhibitor vs Physicians' Choice in Advanced Metastatic Breast Cancer

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 01 Jul 2025

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At a glance

  • Drugs SV-BR-1-GM breast cancer vaccine BriaCell Therapeutics (Primary) ; Cyclophosphamide; Interferon; Retifanlimab
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms ASTRO-VAC CNS; BRIA-ABC
  • Sponsors BriaCell Therapeutics Corp

Most Recent Events

  • 24 Jun 2025 According to a BriaCell Therapeutics Corp media release, the independent Data Safety Monitoring Board (DSMB) has completed its third scheduled safety data review. Following its review, the DSMB raised no safety concerns and recommended that the study continue without modifications.
  • 02 Jun 2025 According to a BriaCell Therapeutics Corp media release, trial in progress data form this trial presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.
  • 23 May 2025 According to a BriaCell Therapeutics Corp media release, data from this study will be presented at the upcoming 2025 American Society of Clinical Oncology (ASCO) Annual Meeting. The company look forward to confirming results in ongoing pivotal Phase 3 study.

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