A Randomized, Double-Blind, Placebo-Controlled Study of Optune (TTFields, 200 kHz) Concomitant With Maintenance TMZ and Pembrolizumab Versus Optune Concomitant With Maintenance TMZ and Placebo for the Treatment of Newly Diagnosed Glioblastoma (EF-41/KEYNOTE D58)
Latest Information Update: 24 Jul 2026
At a glance
- Drugs Pembrolizumab (Primary) ; Temozolomide
- Indications Glioblastoma
- Focus Registrational; Therapeutic Use
- Acronyms Keynote D58
- Sponsors Novocure Limited
Most Recent Events
- 26 Feb 2026 According to Novocure Limited media release, enrollment completion in this study is expected in Q4 2026.
- 02 May 2024 According to a Novocure media release, in March, the FDA approved the Investigational New Drug (IND) application for this trial.
- 30 May 2022 New trial record