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A Phase 1, Parallel-group, 3-part, 2-period, Fixed-sequence, Crossover, Open-label, Nonrandomized, Drug-drug Interaction Study to Assess the Pharmacokinetics of CC-92480 (BMS-986348) After Coadministration With Rifampin and Itraconazole, and Pharmacokinetics of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants

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Trial Profile

A Phase 1, Parallel-group, 3-part, 2-period, Fixed-sequence, Crossover, Open-label, Nonrandomized, Drug-drug Interaction Study to Assess the Pharmacokinetics of CC-92480 (BMS-986348) After Coadministration With Rifampin and Itraconazole, and Pharmacokinetics of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 May 2024

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At a glance

  • Drugs Digoxin (Primary) ; Itraconazole (Primary) ; Mezigdomide (Primary) ; Rifampicin (Primary)
  • Indications Multiple myeloma
  • Focus Pharmacokinetics
  • Sponsors Bristol-Myers Squibb

    • Most Recent Events

    • 29 Mar 2024 Results assessing Physiologically Based Pharmacokinetic (Pbpk) Modeling to Inform the Design of a Clinical Drug-Drug Interaction presented at the 125th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 18 Apr 2023 Status changed from recruiting to completed.
    • 25 Oct 2022 Status changed from not yet recruiting to recruiting.

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