A Phase 1 Open-Label Dose-Escalation Study to Evaluate the Tolerability, DLT, Pharmacokinetics, and Preliminary Efficacy of HF1K16 in Patients With Refractory Solid Tumors
Latest Information Update: 09 Jun 2025
At a glance
- Drugs Tretinoin (Primary)
- Indications Adenocarcinoma; Cholangiocarcinoma; Colon cancer; Glioblastoma; Glioma; Ovarian cancer; Small cell lung cancer; Solid tumours; Thymic epithelial tumour
- Focus Adverse reactions; Pharmacodynamics
- Sponsors HighField Biopharmaceuticals
Most Recent Events
- 30 Apr 2025 Results assessing the safety and preliminary efficacy of ATRA liposomes (HF1K16) in last-stage solid tumor patients presented at the 116th Annual Meeting of the American Association for Cancer Research
- 16 Sep 2024 According to a HighField Biopharmaceuticals media release, as of Sept 1, 2024, 19 patients having Grade II, III and IV tumors have been enrolled.
- 16 Sep 2024 According to a HighField Biopharmaceuticals media release, the Company presented preliminary safety and efficacy findings at the European Society of Medical Oncology (ESMO) Congress in Barcelona, Spain, September 13 -17, 2024.