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A Single-center, Open-label, Single-arm, Fixed-sequence Study to Evaluate the Pharmacokinetic Effects of SHR0302 Tablets on Substrates of CYP3A4, CYP2C8, CYP2C9, CYP2C19 in Healthy Volunteers

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Trial Profile

A Single-center, Open-label, Single-arm, Fixed-sequence Study to Evaluate the Pharmacokinetic Effects of SHR0302 Tablets on Substrates of CYP3A4, CYP2C8, CYP2C9, CYP2C19 in Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Mar 2025

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At a glance

  • Drugs Ivarmacitinib (Primary) ; Midazolam; Omeprazole; Phytomenadione; Repaglinide; Warfarin
  • Indications Rheumatoid arthritis
  • Focus Pharmacokinetics
  • Sponsors Jiangsu Hengrui Medicine Co.

Most Recent Events

  • 21 Dec 2022 Status changed from active, no longer recruiting to completed.
  • 01 Sep 2022 Planned End Date changed from 20 Jul 2022 to 20 Sep 2022.
  • 01 Sep 2022 Planned primary completion date changed from 20 Jul 2022 to 20 Sep 2022.

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