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An Open-Label, Long Term Safety and Efficacy Study of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

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Trial Profile

An Open-Label, Long Term Safety and Efficacy Study of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 05 Jun 2026

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At a glance

  • Drugs Donidalorsen (Primary)
  • Indications Hereditary angioedema
  • Focus Adverse reactions; Registrational
  • Acronyms OASISplus
  • Sponsors Ionis Pharmaceuticals

Most Recent Events

  • 27 Feb 2026 According to an Ionis Pharmaceuticals media release, Results will be presented at the 2026 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting in Philadelphia, PA.
  • 21 Jan 2026 According to an Ionis Pharmaceuticals media release, the European Commission (EC) has approved DAWNZERA (donidalorsen) in the European Union (EU) for the routine prevention of recurrent attacks of hereditary angioedema (HAE) in adults and adolescents aged 12 years and older.
  • 24 Jun 2025 Status changed from recruiting to active, no longer recruiting.

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