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VRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults

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Trial Profile

VRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 27 Oct 2025

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At a glance

  • Drugs MRNA 1215 (Primary)
  • Indications Nipah virus infections
  • Focus Adverse reactions; First in man

Most Recent Events

  • 24 Sep 2024 Status changed from active, no longer recruiting to completed.
  • 12 Sep 2023 Planned End Date changed from 24 Jun 2024 to 1 Oct 2024.
  • 12 Sep 2023 Planned primary completion date changed from 24 Jun 2024 to 1 Oct 2024.

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