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A Multi-center, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Daratumumab in Patients With Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorders (NMOSD)

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A Multi-center, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Daratumumab in Patients With Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorders (NMOSD)

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 04 Apr 2025

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At a glance

  • Drugs Daratumumab (Primary)
  • Indications Neuromyelitis optica
  • Focus Therapeutic Use
  • Acronyms DAWN

Most Recent Events

  • 30 Mar 2025 Status changed from recruiting to active, no longer recruiting.
  • 03 Dec 2024 Planned number of patients changed from 72 to 135.
  • 03 Dec 2024 Planned End Date changed from 1 Oct 2024 to 1 Dec 2025.

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