Trial Profile

A Multicentre Trial Evaluating the Efficacy and Safety of Oral Decitabine Tetrahydrouridine (NDec) in Patients With Sickle Cell Disease

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 01 Jul 2025

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At a glance

Drugs Decitabine/tetrahydrouridine (Primary) ; Hydroxycarbamide
Indications Beta-thalassaemia; Sickle cell anaemia
Focus Therapeutic Use
Acronyms ASCENT1
Sponsors Novo Nordisk

Most Recent Events

14 May 2025 Planned End Date changed from 23 Jul 2025 to 27 Aug 2025.
14 May 2025 Planned primary completion date changed from 10 Dec 2024 to 27 Aug 2025.
14 May 2025 Status changed from recruiting to active, no longer recruiting.

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