Trial Profile

A Phase 1, Open-Label, Single Center, Dose Escalation Study of the Safety and Pharmacokinetics of dMAb AZD5396 and dMAb AZD8076 Delivered as dMAbs in Healthy Adults

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 27 Jan 2026

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At a glance

Drugs AZD 5396 (Primary) ; AZD 8076 (Primary) ; Hyaluronidase; Methylprednisolone
Indications COVID 2019 infections
Focus Adverse reactions; Pharmacokinetics; Proof of concept

Most Recent Events

22 Jan 2026 Status changed from active, no longer recruiting to completed.
21 Oct 2025 According to Inovio Pharmaceuticals media release, result data from Phase 1 proof-of-concept trial evaluating DMAbs for COVID-19 were published in Nature Medicine.
21 Oct 2025 Results presented in the Inovio Pharmaceuticals media release.

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