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Single cell characterization of persistent cells upon treatment with durvalumab (MEDI4736) with or without tremelimumab in MSS and MSI colorectal and endometrial tumors

Trial Profile

Single cell characterization of persistent cells upon treatment with durvalumab (MEDI4736) with or without tremelimumab in MSS and MSI colorectal and endometrial tumors

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Nov 2024

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary)
  • Indications Colorectal cancer; Endometrial cancer
  • Focus Therapeutic Use
  • Acronyms Serpentine
  • Most Recent Events

    • 04 Jun 2024 Results(n=24) discussing data of patients (pts) with refractory ICI-naive MSS EC and CRC treated with Dur plus Trem and the characterization of immune and persistent cells with longitudinal single-cell analyses, presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 16 Jun 2022 New trial record

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