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A Phase 1b/2 Basket Study of ACR-368 as Monotherapy and in Combination With Gemcitabine in Adult Subjects With Platinum-Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma Based on Acrivon OncoSignature® Status

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Trial Profile

A Phase 1b/2 Basket Study of ACR-368 as Monotherapy and in Combination With Gemcitabine in Adult Subjects With Platinum-Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma Based on Acrivon OncoSignature® Status

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 17 Apr 2025

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At a glance

  • Drugs Gemcitabine (Primary) ; Prexasertib (Primary)
  • Indications Adenocarcinoma; Carcinoma; Endometrial cancer; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer; Sarcoma; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Acrivon Therapeutics

Most Recent Events

  • 20 Jun 2023 Planned number of patients changed from 333 to 390.
  • 16 Sep 2022 Status changed from planning to recruiting.
  • 29 Jun 2022 New trial record

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