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A phase I randomized, double-blind, placebo-controlled clinical study assessing safety profile of Lipisense, as well as its pharmacokinetic properties and pharmacodynamic effects for the treatment of severe hypertriglyceridemia as well as the rare disease Familial Chylomicronemia Syndrome (FCS)

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Trial Profile

A phase I randomized, double-blind, placebo-controlled clinical study assessing safety profile of Lipisense, as well as its pharmacokinetic properties and pharmacodynamic effects for the treatment of severe hypertriglyceridemia as well as the rare disease Familial Chylomicronemia Syndrome (FCS)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2024

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At a glance

  • Drugs ANGPTL4 antisense RNA therapy - Leaderna Therapeutics/Lipigon Pharmaceuticals (Primary)
  • Indications Hyperlipoproteinaemia type I; Hypertriglyceridaemia
  • Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics

    • Most Recent Events

    • 06 Nov 2024 According to Secarna Pharmaceuticals media release, company estimates that the study is expected to be fully recruited during the first half of 2025.
    • 01 Jul 2022 New trial record
    • 31 May 2022 According to Secarna Pharmaceuticals media release, Lipigon received approval from the Swedish Medical Products Agency last week to commence this phase I clinical study, first subject has been dosed in this trial

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