Trial Profile

REVERT- Liver Cancer: A Phase 1b/2 Multicenter, Open-label Study to Evaluate the Safety and Efficacy of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 28 Mar 2025

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Pembrolizumab (Primary) ; TTI 101 (Primary)
Indications Liver cancer
Focus Adverse reactions; Therapeutic Use
Sponsors Tvardi Therapeutics

25 Mar 2025 Planned End Date changed from 1 Mar 2025 to 28 Jun 2027.
25 Mar 2025 Planned primary completion date changed from 1 Mar 2025 to 29 Jun 2026.
11 Feb 2025 Planned number of patients changed from 166 to 178.

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