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Phase 1b Study of IDH Inhibition With Enasidenib and MEK Inhibition With Cobimetinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Have Co-Occurring IDH2 and RAS Signaling Gene Mutations

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Trial Profile

Phase 1b Study of IDH Inhibition With Enasidenib and MEK Inhibition With Cobimetinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Have Co-Occurring IDH2 and RAS Signaling Gene Mutations

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 08 Oct 2025

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At a glance

Most Recent Events

  • 16 Sep 2025 Status changed from suspended to active, no longer recruiting.
  • 03 Jun 2025 Status changed from recruiting to suspended, due to drug availability.
  • 03 Jun 2025 Planned End Date changed from 2 May 2025 to 3 May 2027.

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