A Phase 3, Multi-center, Randomized, Double-blind Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Latest Information Update: 19 May 2025
At a glance
- Drugs Aficamten (Primary) ; Metoprolol succinate
- Indications Hypertrophic cardiomyopathy
- Focus Registrational; Therapeutic Use
- Acronyms MAPLE-HCM
- Sponsors Cytokinetics
Most Recent Events
- 13 May 2025 Primary endpoint (Change in peak oxygen uptake (pVO2) by cardiopulmonary exercise testing (CPET)) has been met.
- 13 May 2025 According to a Cytokinetics media release, the full results from MAPLE-HCM will be presented at an upcoming medical conference.
- 13 May 2025 Results presented in a Cytokinetics media release.