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Pilot Trial of Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

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Trial Profile

Pilot Trial of Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Jul 2025

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At a glance

  • Drugs Colestyramine (Primary) ; Leflunomide (Primary) ; Steroids
  • Indications Graft-versus-host disease
  • Focus Adverse reactions

Most Recent Events

  • 04 Jul 2025 Planned End Date changed from 5 Jul 2025 to 5 Jan 2027.
  • 04 Jul 2025 Planned primary completion date changed from 5 Jul 2025 to 5 Jan 2027.
  • 19 Jun 2023 Planned End Date changed from 8 Oct 2023 to 5 Jul 2025.

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