Trial Profile

A Phase 1 Study of VAC85135, a Neoantigen Vaccine Regimen, Concurrently Administered With Ipilimumab for the Treatment of Myeloproliferative Neoplasms

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 09 Apr 2025

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At a glance

Drugs Ipilimumab (Primary) ; VAC-85135 (Primary)
Indications Essential thrombocythaemia; Myelofibrosis; Myeloproliferative disorders; Polycythaemia vera
Focus Adverse reactions; First in man
Sponsors Bristol-Myers Squibb; Janssen Research & Development

Most Recent Events

04 Apr 2025 Planned primary completion date changed from 20 Feb 2025 to 24 Jun 2025.
08 Jan 2025 Planned End Date changed from 27 Nov 2027 to 10 Oct 2025.
08 Jan 2025 Planned primary completion date changed from 16 Jan 2026 to 20 Feb 2025.

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