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The Effect of Imlunestrant on CYP2C8, CYP2C19, CYP2D6, P-gp, and BCRP Activity and the Effect of P-gp Inhibition on Imlunestrant Pharmacokinetics in Healthy Women of Non-childbearing Potential

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Trial Profile

The Effect of Imlunestrant on CYP2C8, CYP2C19, CYP2D6, P-gp, and BCRP Activity and the Effect of P-gp Inhibition on Imlunestrant Pharmacokinetics in Healthy Women of Non-childbearing Potential

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Nov 2022

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At a glance

  • Drugs Dextromethorphan (Primary) ; Digoxin (Primary) ; Imlunestrant (Primary) ; Omeprazole (Primary) ; Quinidine (Primary) ; Repaglinide (Primary) ; Rosuvastatin (Primary)
  • Indications Breast cancer; Endometrial cancer
  • Focus Pharmacokinetics
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 23 Nov 2022 Status changed from active, no longer recruiting to completed.
  • 18 Oct 2022 Status changed from recruiting to active, no longer recruiting.
  • 19 Jul 2022 Status changed from not yet recruiting to recruiting.

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