Phase 2 Randomized Open-label Multicenter Study of Combination of ONC-392 and Pembrolizumab for the Treatment of Patients with Platinum Resistant Ovarian Cancer (PROC)
Latest Information Update: 12 Aug 2025
At a glance
- Drugs Gotistobart (Primary) ; Pembrolizumab (Primary)
- Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
- Focus Adverse reactions; Therapeutic Use
- Acronyms PRESERVE-004
- Sponsors OncoC4
Most Recent Events
- 29 Jul 2025 Planned primary completion date changed from 30 Jun 2025 to 30 Oct 2025.
- 04 Nov 2024 According to a BioNTech media release, In September 2024, preliminary data from this trial were presented at ESMO. The data suggest encouraging preliminary clinical activity and a manageable tolerability profile with no new safety signals detected for the combination.
- 24 Oct 2024 Status changed from recruiting to active, no longer recruiting.