Trial Profile

A PHASE 1, RANDOMIZED, OPEN-LABEL STUDY IN HEALTHY PARTICIPANTS TO ESTIMATE THE BIOAVAILABILITY OF TWO NEW ENCORAFENIB FORMULATIONS RELATIVE TO THE CURRENT FORMULATION AND TO EVALUATE THE EFFECT OF A PROTON-PUMP INHIBITOR ON ENCORAFENIB PLASMA PHARMACOKINETICS

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 26 Feb 2024

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At a glance

Drugs Encorafenib (Primary) ; Rabeprazole (Primary)
Indications Brain metastases; Colorectal cancer; Glioma; Haematological malignancies; Malignant melanoma; Multiple myeloma; Non-small cell lung cancer; Solid tumours; Thyroid cancer
Focus Pharmacokinetics
Acronyms ERBA
Sponsors Pfizer

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