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A Phase 1/2 Open-label, First-in-human, Dose Escalation and Expansion Study for the Evaluation of Safety, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of SAR444200-based Regimen in Participants With Advanced Solid Tumors

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Trial Profile

A Phase 1/2 Open-label, First-in-human, Dose Escalation and Expansion Study for the Evaluation of Safety, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of SAR444200-based Regimen in Participants With Advanced Solid Tumors

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 20 Jan 2026

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At a glance

  • Drugs Atezolizumab (Primary) ; SAR-444200 (Primary)
  • Indications Liver cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Sanofi

Most Recent Events

  • 14 Jan 2026 Status changed from active, no longer recruiting to discontinued.
  • 24 Nov 2025 Planned End Date changed from 25 Dec 2025 to 22 Dec 2025.
  • 24 Nov 2025 Planned primary completion date changed from 25 Dec 2025 to 22 Dec 2025.

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