Study to Assess the Safety and Efficacy of Evexomostat (SDX-7320) in Combination With A PI3K or Akt Inhibitor Plus Fulvestrant in Patients With HR+, HER2-, Metastatic Breast Cancer With PI3K Pathway Alteration(s)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 28 Jan 2025

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At a glance

Drugs Alpelisib (Primary) ; Capivasertib (Primary) ; Evexomostat (Primary) ; Fulvestrant (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer
Focus Adverse reactions; Proof of concept
Acronyms Amelia-1
Sponsors SynDevRx, Inc

Most Recent Events

06 Jun 2023 Trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology
10 Dec 2022 Trial design presented at the 45th Annual San Antonio Breast Cancer Symposium.
21 Oct 2022 Status changed from not yet recruiting to recruiting.

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