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Phase 2, Randomized, Open-Label Study to Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Patients With Locally Advanced Unresectable or Metastatic Esophageal Squamous Cell Carcinoma That Progressed on or After Anti-PD-(L)1 Antibody Therapy

Trial Profile

Phase 2, Randomized, Open-Label Study to Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Patients With Locally Advanced Unresectable or Metastatic Esophageal Squamous Cell Carcinoma That Progressed on or After Anti-PD-(L)1 Antibody Therapy

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 20 Jun 2025

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At a glance

  • Drugs Docetaxel (Primary) ; Irinotecan (Primary) ; Sitravatinib (Primary) ; Tislelizumab (Primary)
  • Indications Oesophageal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Sponsors BeOne Medicines

Most Recent Events

  • 01 Mar 2024 Status changed from active, no longer recruiting to discontinued.
  • 08 Nov 2023 Status changed from recruiting to active, no longer recruiting.
  • 02 Nov 2023 Status changed from active, no longer recruiting to recruiting.

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