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A Single and Multiple Dose Study to Evaluate Safety, Pharmacokinetics, and Treatment Effect of Intravitreal AVD-104 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

Trial Profile

A Single and Multiple Dose Study to Evaluate Safety, Pharmacokinetics, and Treatment Effect of Intravitreal AVD-104 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 10 Jan 2025

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At a glance

  • Drugs AVD 104 (Primary) ; Avacincaptad pegol
  • Indications Age-related macular degeneration; Dry macular degeneration
  • Focus Adverse reactions; First in man; Pharmacokinetics; Registrational
  • Acronyms SIGLEC
  • Sponsors Aviceda Therapeutics

Most Recent Events

  • 07 Jan 2025 According to an Aviceda Therapeutics media release,the company announced the closing of a $207.5 million Series C financing. Proceeds will support the ongoing Phase 2b/3 and planned pivotal Phase 3 clinical trial for AVD-104 in geographic atrophy (GA).
  • 16 Dec 2024 Planned End Date changed from 1 Jun 2026 to 1 Sep 2026.
  • 16 Dec 2024 Planned primary completion date changed from 1 Jun 2025 to 1 Sep 2025.

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