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Surufatinib and Sintilimab in Combination With Capecitabine in Patients With Previously Treated Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma : a Single-arm, a Single-center , Phase 2 Trial

Trial Profile

Surufatinib and Sintilimab in Combination With Capecitabine in Patients With Previously Treated Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma : a Single-arm, a Single-center , Phase 2 Trial

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Jun 2025

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At a glance

  • Drugs Capecitabine (Primary) ; Regorafenib (Primary) ; Sintilimab (Primary) ; Surufatinib (Primary)
  • Indications Adenocarcinoma; Appendiceal cancer; Carcinoma; Intestinal cancer
  • Focus Therapeutic Use

Most Recent Events

  • 30 Apr 2025 Results (data cut off December 31, 2024, n=9) assessing efficacy and safety of surufatinib, a multi-target tyrosine kinase inhibitor targeting VEGFR1-3, FGFR1, and CSF-1R, in combination with sintilimab and capecitabine for advanced SBA and appendiceal carcinoma, presented at the 116th Annual Meeting of the American Association for Cancer Research.
  • 28 Jul 2022 New trial record

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