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RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)

Trial Profile

RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Feb 2024

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At a glance

  • Drugs Ezetimibe/rosuvastatin (Primary) ; Rosuvastatin
  • Indications Cardiovascular disorders; Hypercholesterolaemia
  • Focus Therapeutic Use
  • Acronyms RACING
  • Most Recent Events

    • 22 Feb 2024 Results of post-hoc sub-group analysis assessing safety and efficacy of a moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with metabolic syndrome (MetS) and atherosclerotic cardiovascular disease, published in the Diabetes, Obesity and Metabolism.
    • 01 Dec 2023 Results of post hoc analysis assessing the heterogeneities of efficacy and safety of moderate-intensity statin plus ezetimibe combination therapy versus high-intensity statin monotherapy according to baseline LDL-C levels, published in the Atherosclerosis.
    • 28 Aug 2023 Results of a prespecified subgroup analysis comparing the effects of moderate-intensity statin plus ezetimibe combination therapy to high-intensity statin monotherapy based on baseline low-density lipoprotein cholesterol (LDL-C) levels, presented at the ESC Congress 2023 - Annual Congress of the European Society of Cardiology.

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